ACADEMY SERIES · EPISODE 33Pharma
Why Tablets Stick and Coatings Fail
If tablet powder clumps, tablets come out brittle or the coating will not sit evenly, the room air deserves a look too. We cover the effects of too much moisture and of too dry air, how the target humidity is set and how it is held.
Published: 9 November 2026Narration: Turkish and English2:31
In this video
- Most pharmaceutical raw materials take up moisture; each blend reaches its best flow at a particular humidity.
- With too much moisture particles clump and tablets can turn soft and brittle.
- With air too dry, dusting and static increase and tablets do not bind well.
- Water based coating solutions are harder to apply evenly in humid conditions.
- Target values come from the supplier or laboratory analysis, and are held with low dew point dry air.
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